Hepatitis B virus vaccines: Some cryptic issues
نویسندگان
چکیده
منابع مشابه
STUDIES ON HEPATITIS B VACCINES
HBs vaccines were prepared by three different methods: 1) Heat inactivation (Krugman, et.al 1971)2) Ammonium sulphate precipitation followed by column chromatography (Sephadex G-200) 3) PEG-6000 (polyethylene glycol) precipitation followed by column chromatography using Sephadex G-200. Their efficacy was studied in guinea pigs, and the results compared with commercial Japanese vaccine (Gr...
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Human hepatitis B virus (HBV) causes a communicable disease that spreads worldwide and has brought about considerable economic losses due to human mortality and morbidity. HBV fails to reproduce in both cell cultures and laboratory animals; however, it is known that excess virion surface protein named hepatitis B surface antigen (HBsAg) is produced during viral replication and circulates in the...
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ژورنال
عنوان ژورنال: Hepatology
سال: 1998
ISSN: 0270-9139,1527-3350
DOI: 10.1002/hep.510280139